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Meningioma | Treatment | Targeted Therapy
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Limon D, Amiel A, Even Haim S, Gordon N, Tschernichovsky R,
Stemmer S, Gal O, Laviv Y, Kanner A, Siegal T, Yust-Katz S.
A
phase II, open-label, single-arm trial of pembrolizumab for
recurrent meningioma and solitary fibrous tumor.
Neurooncol
Adv. 2024 Sep 16;6(1):vdae154. doi:
10.1093/noajnl/vdae154. PMID:
39429970. Interventional study. ˍ
Hajikarimloo B, Hasanzade A, Sabbagh Alvani M, Habibi MA.
Application of bevacizumab in the
management of meningiomas: a systematic review and meta-analysis.
Neurosurg
Rev. 2024 Sep 27;47(1):692. doi:
10.1007/s10143-024-02889-w. PMID:
39327340. Review˰ ˍ
Bosio A, Cerretti G, Padovan M, Del Bianco P, Polano M,
Mandruzzato S, Indraccolo S, Manara R, Librizzi G, Caccese M,
Corrà M, Maccari M, Lonardi S, De Salvo GL, Lombardi G.
Regorafenib versus local standard of
care in patients with grade 2-3 meningioma no longer eligible for
loco-regional treatments: a phase II randomized controlled trial
(the MIRAGE study).
Trials.
2025 Aug 4;26(1):268. doi:
10.1186/s13063-025-08997-2. PMID:
40759981. Interventional study protocol. ˍ
AI
Overview
Kaley TJ, Grommes C, Coffee E, Young RJ, Morrison T, Daher A,
Schaff LR, Deng Y, Nandakumar S, Diamond EL, DeAngelis LM,
Panageas KS, Gavrilovic I, Lin A, Pentsova E, Stone J, Santomasso
BD, Piotrowski AF, Nair S, Schultz N, Reiner AS, Mellinghoff IK.
Multicenter basket trial for Central
Nervous System tumors identifies activity of the CDK4/6 inhibitor
abemaciclib in recurrent meningioma.
Neuro
Oncol. 2025 Aug 16:noaf184. doi:
10.1093/neuonc/noaf184. PMID:
40842355. Interventional
study˰ ˍ
Tsao AS, Song Z, Ho AL, Mehnert JM, Ivy P, Gray RJ, Wang V,
McShane LM, Rubinstein LV, Patton DR, Williams PM, Hamilton SR,
Takebe N, Ajumally R, Silhavy J, Rahmanian S, Das B, Chen L,
Karlovich C, Lococo JS, Tricoli JV, Conley BA, Arteaga CL, Harris
LN, O'Dwyer PJ, Chen AP, Flaherty KT.
Phase
II Study of Vismodegib in Patients With SMO-
or PTCH1-Mutated
Tumors: Results From the National Cancer Institute Molecular
Analysis for Therapy Choice Eastern Cooperative Oncology
Group-American College of Radiology Imaging Network Trial (EAY131)
Subprotocol T.
JCO
Precis Oncol. 2025 Oct 9;9:e2500119. doi:
10.1200/PO-25-00119. PMID:
41066729. Interventional study˰
ˍ