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Oligodendroglioma | Treatment | Chemotherapy

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Kacimi SEO, Dehais C, Feuvret L, Chinot O, Carpentier C, Bronnimann C, Vauleon E, Djelad A, Cohen-Jonathan Moyal E, Langlois O, Campone M, Ducloie M, Noel G, Cuzzubbo S, Taillandier L, Ramirez C, Younan N, Menei P, Dhermain F, Desenclos C, Ghiringhelli F, Bourg V, Ricard D, Faillot T, Appay R, Tabouret E, Nichelli L, Mathon B, Thomas A, Tran S, Bielle F, Alentorn A, Iorgulescu JB, Boëlle PY, Labreche K, Hoang-Xuan K, Sanson M, Idbaih A, Figarella-Branger D, Ducray F, Touat M; POLA Network.
Survival Outcomes Associated With First-Line Procarbazine, CCNU, and Vincristine or Temozolomide in Combination With Radiotherapy in IDH-Mutant 1p/19q-Codeleted Grade 3 Oligodendroglioma.
J Clin Oncol. 2024 Oct 2:JCO2400049. doi: 10.1200/JCO.24.00049. PMID: 39356975. Observational study˰ ˍ

*Rincon-Torroella J, Rakovec M, Kalluri AL, Jiang K, Weber-Levine C, Parker M, Raj D, Materi J, Sepehri S, Ferres A, Schreck KC, Aldecoa I, Lucas CG, Sair HI, Redmond KJ, Holdhoff M, Weingart J, Brem H, Sánchez JJG, Ye X, Bettegowda C.
Impact of upfront adjuvant chemoradiation on survival in patients with molecularly defined oligodendroglioma: the benefits of PCV over TMZ.
J Neurooncol. 2024 Oct 9. doi: 10.1007/s11060-024-04829-6. PMID: 39382617. Observational study˰ ˍ

Santos MDC, Rodrigues NMV, Gibram F, Gouhie FA, Campos ACP, de Assis DV, Formentin C, Feher O, de Souza E Silva ARN, Hanna SA, Chung C, Barbosa CC, Moraes FY, Maldaun MVC.
Adjuvant chemoradiotherapy with procarbazine, lomustine, and vincristine (PCV) or temozolomide for 1p/19q Co-deleted anaplastic oligodendroglioma: a systematic review and network meta-analysis.
BMC Cancer. 2025 Nov 18;25(1):1779. doi: 10.1186/s12885-025-15085-w. PMID: 41254593. Review; Meta-Analysis. ˍ

Duran G, Pichardo-Rojas D, Ali AH, Passias P, Downes A, Ray WZ, Zipfel GJ, Shakir HJ, Bauer A, Jea A, Dunn IF, Zuccato JA, Graffeo CS, Janjua MB.
Comparing Isocitrate Dehydrogenase Inhibitors with Procarbazine, Lomustine, and Vincristine Chemotherapy for Oligodendrogliomas.
Cancers (Basel). 2025 Dec 4;17(23):3880. doi: 10.3390/cancers17233880. PMID: 41375081. Review. ˍ