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Pediatric-type diffuse gliomas | Treatment | Clinical trials | Vemurafenib

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2026

Nicolaides T, Hoogendijk R, Jaeger-Krause M, Dhall G, Goldman S, Gajjar A, Kilburn L, Leary S, Minturn J, Whipple N, Ramakrishnan D, Long-Boyle J, Aboian M, Prados M, Molinaro AM, Mueller S.
Efficacy Study of Vemurafenib in Children With Recurrent or Progressive BRAF^V600E- or BRAF^InsT-Mutant Brain Tumors: PNOC002.
JCO Precis Oncol. 2026 Sep 23;10(9):e2600558. doi: 10.1200/PO-26-00558. PMID: 42777179. Trial registration ID: PNOC002. ˍ