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Current
Neuro-Oncology
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Volume
22 Number 20
31 October 2020
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Home
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Current
Neuro-Oncology >
Volume
22, Year 2020 >
Number 20, 31 October
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Awada
G, Ben Salama L, De Cremer J, Schwarze JK, Fischbuch L, Seynaeve
L, Du Four S, Vanbinst AM, Michotte A, Everaert H, Rogiers A,
Theuns P, Duerinck J, Neyns B.
Axitinib
plus avelumab in the treatment of recurrent glioblastoma: a
stratified, open-label, single-center phase 2 clinical trial
(GliAvAx).
J
Immunother Cancer. 2020 Oct 16, 2020;8(2):e001146∟.
doi: 10.1136/jitc-2020-001146∟.
PMID: 33067319∟.
Interventional
study. ˍ
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Li
G, Wu F, Zeng F, Zhai Y, Feng Y, Chang Y, Wang D, Jiang T, Zhang
W.
A
novel DNA repair-related nomogram predicts survival in low-grade
gliomas.
CNS
Neurosci Ther. 2020 Oct 16, 2021;27(2):186-195∟.
doi:
10.1111/cns.13464∟.
PMID:
33063446∟.
Observational
study.
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Kondo
N, Hikida M, Nakada M, Sakurai Y, Hirata E, Takeno S, Suzuki M.
Glioma
Stem-Like Cells Can Be Targeted in Boron Neutron Capture Therapy
with Boronophenylalanine.
Cancers
(Basel).
2020 Oct 19, 2020;12(10):3040∟.
doi: 10.3390/cancers12103040∟.
PMID: 33086625∟.
Laboratory
investigation. ˍ
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Seaman
SC, Bathla G, Park BJ, Woodroffe RW, Smith M, Menezes AH, Noeller
J, Yamaguchi S, Hitchon PW.
MRI
characteristics and resectability in spinal cord glioma.
Clin
Neurol Neurosurg. 2020 Oct 19, 2021;200:106321∟.
doi: 10.1016/j.clineuro.2020.106321∟.
PMID: 33268194∟.
Observational
study.
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Brigliadori
G, Goffredo G, Bartolini D, Tosatto L, Gurrieri L, Mercatali L,
Ibrahim T.
Influence
of Intratumor Heterogeneity on the Predictivity of MGMT Gene
Promoter Methylation Status in Glioblastoma.
Front
Oncol. 2020 Oct 20, 2020;10:533000∟.
doi: 10.3389/fonc.2020.533000∟.
PMID: 33194592∟.
Observational study. ˍ
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Irfan
N, Samuel E, Rafi Ranjha F, Waheed A, Abu Bakar M, Usman S, Butt
S, Rashid A, Yousaf I.
Toxicity
Profile of Procarbazine Lomustine and Vincristine Chemotherapy in
Low-Grade Glioma - Retrospective Review.
Cureus.
2020 Oct 20, 2020;12(10):e11070∟.
doi: 10.7759/cureus.11070∟.
PMID: 33224664∟.
Observational
study. ˍ
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Hu
C, Lin Q, Liu C, Liu J, Chen X, Li X, Zhao G, Zhang L.
Bioequivalence
study of 20-mg and 100-mg temozolomide capsules (TOZ309 and
Temodal®)
in glioma patients in China.
Cancer
Chemother Pharmacol. 2020 Oct 21, 2020;86(6):793-801∟.
doi: 10.1007/s00280-020-04175-0∟.
PMID: 33089408∟.
Interventional
study. ˍ
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Khalafallah
AM, Jimenez AE, Shah PP, Brem H, Mukherjee D.
Effect
of radiation therapy on overall survival following subtotal
resection of adult pilocytic astrocytoma.
J
Clin Neurosci. 2020 Oct 21. 2020;81:340-345∟.
doi: 10.1016/j.jocn.2020.10.020∟.
PMID: 33222942∟.
Observational study. ˍ
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Makarevic
A, Rapp C, Dettling S, Reuss D, Jungk C, Abdollahi A, von Deimling
A, Unterberg A, Herold-Mende C, Warta R.
Increased
Radiation-Associated T-Cell Infiltration in Recurrent IDH-Mutant
Glioma.
Int
J Mol Sci. 2020 Oct 21, 2020;21(20):7801∟.
doi: 10.3390/ijms21207801∟.
PMID:
33096928∟.
Laboratory
investigation.
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Wu
W, Deng Z, Alafate W, Wang Y, Xiang J, Zhu L, Li B, Wang M, Wang
J.
Preoperative
Prediction Nomogram Based on Integrated Profiling for Glioblastoma
Multiforme in Glioma Patients.
Front
Oncol. 2020 Oct 21, 2020;10:1750∟.
doi: 10.3389/fonc.2020.01750∟.
PMID: 33194573∟.
Observational study. ˍ
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Yan
J, Zhang S, Li KK, Wang W, Li K, Duan W, Yuan B, Wang L, Liu L,
Zhan Y, Pei D, Zhao H, Sun T, Sun C, Wang W, Liu Z, Hong X, Wang
X, Guo Y, Li W, Cheng J, Liu X, Ng HK, Li Z, Zhang Z.
Incremental
prognostic value and underlying biological pathways of radiomics
patterns in medulloblastoma.
EBioMedicine.
2020 Oct 21, 2020;61:103093∟.
doi: 10.1016/j.ebiom.2020.103093∟.
PMID: 33096488∟.
Observational
study.
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Butenschoen
VM, Hubertus V, Janssen IK, Onken J, Wipplinger C, Mende KC,
Eicker SO, Kehl V, Thomé C, Vajkoczy P, Schaller K, Gempt
J, Meyer B, Wostrack M.
Surgical
treatment and neurological outcome of infiltrating intramedullary
astrocytoma WHO II-IV: a multicenter retrospective case series.
J
Neurooncol. 2020 Oct 22, 2021;151(2):181-191∟.
doi: 10.1007/s11060-020-03647-w∟.
PMID: 33094355∟.
Observational
study.
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Dastghaib
S, Shojaei S, Mostafavi-Pour Z, Sharma P, Patterson JB, Samali A,
Mokarram P, Ghavami S.
Simvastatin
Induces Unfolded Protein Response and Enhances
Temozolomide-Induced Cell Death in Glioblastoma Cells.
Cells.
2020 Oct 22, 2020;9(11):E2339∟.
doi: 10.3390/cells9112339∟.
PMID:
33105603∟.
Laboratory
investigation.
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Dorfer
C, Czech T, Gojo J, Hosmann A, Peyrl A, Azizi AA, Kasprian G,
Dieckmann K, Filbin MG, Haberler C, Roessler K, Slavc
I.
Infiltrative
gliomas of the thalamus in children: the role of surgery in the
era of H3 K27M mutant midline gliomas.
Acta
Neurochir
(Wien).
2020 Oct 22, 2021;163(7):2025-2035∟.
doi: 10.1007/s00701-020-04589-y∟.
PMID: 33090244∟.
Observational
study. ˍ
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Hill
RM, Richardson S, Schwalbe EC, Hicks D, Lindsey JC, Crosier S,
Rafiee G, Grabovska Y, Wharton SB, Jacques TS, Michalski A, Joshi
A, Pizer B, Williamson D, Bailey S, Clifford SC.
Time,
pattern, and outcome of medulloblastoma relapse and their
association with tumour biology at diagnosis and therapy: a
multicentre cohort study.
Lancet
Child Adolesc Health. 2020 Oct 22, 2020;4(12):865-874∟.
doi: 10.1016/S2352-4642(20)30246-7∟.
PMID:
33222802∟.
Observational study. ˍ
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Kong
Z, Jiang C, Zhang Y, Liu S, Liu D, Liu Z, Chen W, Liu P, Yang T,
Lyu Y, Zhao D, You H, Wang Y, Ma W, Feng F.
Thin-Slice
Magnetic Resonance Imaging-Based Radiomics Signature Predicts
Chromosomal 1p/19q Co-deletion Status in Grade II and III
Gliomas.
Front
Neurol. 2020 Oct 22, 2020;11:551771∟.
doi: 10.3389/fneur.2020.551771∟.
PMID: 33192984∟.
Observational study. ˍ
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Franco
P, Delev D, Cipriani D, Neidert N, Kellner E, Masalha W, Mercas B,
Mader I, Reinacher P, Weyerbrock A, Fung C, Beck J, Heiland DH,
Schnell O.
Surgery
for IDH1/2 wild-type glioma invading the corpus callosum.
Acta
Neurochir
(Wien).
2020 Oct 23, 2021;163(4):937-945∟.
doi: 10.1007/s00701-020-04623-z∟.
PMID: 33095353∟.
Observational
study. ˍ
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Niu
L, Feng WH, Duan CF, Liu YC, Liu JH, Liu XJ.
The
Value of Enhanced MR Radiomics in Estimating the IDH1 Genotype in
High-Grade Gliomas.
Biomed
Res Int. 2020 Oct 24, 2020;2020:4630218∟.
doi: 10.1155/2020/4630218∟.
PMID: 33163535∟.
Observational study. ˍ
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Pan
ZQ, Zhang SJ, Wang XL, Jiao YX, Qiu JJ.
Machine
Learning Based on a Multiparametric and Multiregional Radiomics
Signature Predicts Radiotherapeutic Response in Patients with
Glioblastoma.
Behav
Neurol. 2020 Oct 24, 2020;2020:1712604∟.
doi: 10.1155/2020/1712604∟.
PMID: 33163122∟.
Observational study.
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Morana
G, Tortora D, Bottoni G, Puntoni M, Piatelli G, Garibotto F, Barra
S, Giannelli F, Cistaro A, Severino M, Verrico A, Milanaccio C,
Massimino M, Garrè ML, Rossi A, Piccardo A.
Correlation
of multimodal 18F-DOPA
PET and conventional MRI with treatment response and survival in
children with diffuse intrinsic pontine gliomas.
Theranostics.
2020 Oct 25, 2020;10(26):11881-11891∟.
doi: 10.7150/thno.50598∟.
PMID: 33204317∟.
Observational study. ˍ
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Öksüz
E, Görgİşen G, Özdemİr H, Gülaçar
İM, Oto G.
Effect
of paracetamol in the proliferation of glioblastoma cell line: The
role of apoptosis, COX-2 and cyclin B expressions.
Turk
Neurosurg. 2020 Oct 26, 2021;31(1):46-50∟.
doi: 10.5137/1019-5149.JTN.27866-19.7∟.
PMID: 33216331∟.
Laboratory
investigation.
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Prabhu
RS, Ward MC, Heinzerling JH, Corso CD, Buchwald ZS, Dhakal R,
Asher AL, Sumrall AL, Burri SH.
The
Association Between Radiation Therapy Dose and Overall Survival in
Patients With Intracranial Infiltrative Low-Grade Glioma Treated
With Concurrent and/or Adjuvant Chemotherapy.
Adv
Radiat Oncol. 2020 Oct 26, 2021;6(1):100577∟.
doi: 10.1016/j.adro.2020.09.017∟.
PMID: 33665485∟.
Observational study. ˍ
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Escudero
L, Llort A, Arias A, Diaz-Navarro A, Martínez-Ricarte F,
Rubio-Perez C, Mayor R, Caratù G, Martínez-Sáez
E, Vázquez-Méndez É, Lesende-Rodríguez
I, Hladun R, Gros L, Ramón Y Cajal S, Poca MA, Puente XS,
Sahuquillo J, Gallego S, Seoane J.
Circulating
tumour DNA from the cerebrospinal fluid allows the
characterisation and monitoring of medulloblastoma.
Nat
Commun. 2020 Oct 27, 2020;11(1):5376∟.
doi: 10.1038/s41467-020-19175-0∟.
PMID:
33110059∟.
Laboratory
investigation.
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Sakai
Y, Yang C, Kihira S, Tsankova N, Khan F, Hormigo A, Lai A,
Cloughesy T, Nael K.
MRI
Radiomic Features to Predict IDH1 Mutation Status in Gliomas: A
Machine Learning Approach using Gradient Tree Boosting.
Int
J Mol Sci. 2020 Oct 27, 2020;21(21):E8004∟.
doi: 10.3390/ijms21218004∟.
PMID: 33121211∟.
Observational study. ˍ
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Xue
C, Zhang B, Deng J, Liu X, Li S, Zhou J.
Differentiating
Giant Cell Glioblastoma from Classic Glioblastoma With
Diffusion-Weighted Imaging.
World
Neurosurg. 2020 Oct 27, 2021;146:e473-e478∟.
doi: 10.1016/j.wneu.2020.10.125∟.
PMID: 33127573∟.
Observational study. ˍ
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Cataldi
S, Arcuri C, Lazzarini A, Nakashidze I, Ragonese F, Fioretti B,
Ferri I, Conte C, Codini M, Beccari T, Curcio F, Albi E.
Effect
of 1α,25(OH)2
Vitamin
D3
in
Mutant P53 Glioblastoma Cells: Involvement of Neutral
Sphingomyelinase1.
Cancers
(Basel).
2020 Oct 28, 2020;12(11):3163∟.
doi: 10.3390/cancers12113163∟.
PMID: 33126474∟.
Laboratory investigation. ˍ
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Tzaridis
T, Schäfer N, Weller J, Steinbach JP, Schlegel U, Seidel S,
Sabel M, Hau P, Seidel C, Krex D, Goldbrunner R, Tonn JC, Grauer
O, Kebir S, Schneider M, Schaub C, Vatter H, Coch C, Glas M,
Fimmers R, Pietsch T, Reifenberger G, Herrlinger U, Felsberg J.
MGMT
promoter methylation analysis for allocating combined CCNU/TMZ
chemotherapy: Lessons learned from the CeTeG/NOA-09 trial.
Int
J Cancer. 2020 Oct 28, 2021;148(7):1695-1707∟.
doi: 10.1002/ijc.33363∟.
PMID: 33113214∟.
Interventional
study. ˍ
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Climans
SA, Macdonald DR, Sutherland DE, Mason WP.
Prolonged
response to vismodegib in a patient with systemic medulloblastoma
metastases.
BMJ
Case Rep. 2020 Oct 29, 2020;13(10):e236406∟.
doi: 10.1136/bcr-2020-236406∟.
PMID: 33122230∟.
Case
report. ˍ
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Cloughesy
TF, Petrecca K, Walbert T, Butowski N, Salacz M, Perry J, Damek D,
Bota D, Bettegowda C, Zhu JJ, Iwamoto F, Placantonakis D, Kim L,
Elder B, Kaptain G, Cachia D, Moshel Y, Brem S, Piccioni D,
Landolfi J, Chen CC, Gruber H, Rao AR, Hogan D, Accomando W,
Ostertag D, Montellano TT, Kheoh T, Kabbinavar F, Vogelbaum MA.
Effect
of Vocimagene Amiretrorepvec in Combination With Flucytosine vs
Standard of Care on Survival Following Tumor Resection in Patients
With Recurrent High-Grade Glioma: A Randomized Clinical
Trial.
JAMA
Oncol. 2020 Oct 29, 2020;6(12):1939-1946∟.
doi: 10.1001/jamaoncol.2020.3161∟.
PMID: 33119048∟.
Interventional
study. ˍ
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Coomans
MB, Dirven L, Aaronson NK, Baumert BG, van den Bent M, Bottomley
A, Brandes AA, Chinot O, Coens C, Gorlia T, Herrlinger U,
Keime-Guibert F, Malmström A, Martinelli F, Sloan JA, Stupp
R, Talacchi A, Weller M, Wick W, Reijneveld JC, Taphoorn
MJB.
Calculating
the net clinical benefit in neuro-oncology clinical trials using
two methods: quality-adjusted survival effect sizes and joint
modeling.
Neurooncol
Adv. 2020 Oct 29, 2020;2(1):vdaa147∟.
doi: 10.1093/noajnl/vdaa147∟.
PMID: 33409496∟.
Observational
study.
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Diao
S, Gu C, Zhang H, Yu C.
Immune
cell infiltration and cytokine secretion analysis reveal a
non-inflammatory microenvironment of medulloblastoma.
Oncol
Lett. 2020 Oct 29, 2020;20(6):397∟.
doi: 10.3892/ol.2020.12260∟.
PMID: 33193857∟.
Laboratory investigation. ˍ
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Hsu
PYH, Folkman F, Ghosh S, de Robles P, Leckie C, Dersch-Mills D,
Coppens R, Chambers C.
Actual
body weight dosing of temozolomide and overall survival in
patients with glioblastoma.
J
Oncol Pharm Pract. 2020 Oct 29, 2021;27(7):1723-1729∟.
doi: 10.1177/1078155220968613∟.
PMID: 33121351∟.
Observational
study. ˍ
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Chia
BSH, Leong JY, Ong ALK, Lim C, Poon SH, Chua MLK, Chua KLM,
Kusumawidjaja G, Chua ET, Wong FY, Lee TS.
Randomised
prospective phase II trial in multiple brain metastases comparing
outcomes between hippocampal avoidance whole brain radiotherapy
with or without simultaneous integrated boost: HA-SIB-WBRT study
protocol.
BMC
Cancer. 2020 Oct 30, 2020;20(1):1045∟.
doi: 10.1186/s12885-020-07565-y∟.
PMID: 33126867∟.
Protocol.
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Ding
XC, Wang LL, Zhu YF, Li YD, Nie SL, Yang J, Liang H, Weichselbaum
RR, Yu JM, Hu M.
The
Change of Soluble Programmed Cell Death-Ligand 1 in Glioma
Patients Receiving Radiotherapy and Its Impact on Clinical
Outcomes.
Front
Immunol. 2020 Oct 30, 2020;11:580335∟.
doi: 10.3389/fimmu.2020.580335∟.
PMID: 33224142∟.
Observational study. ˍ
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Ostrom
QT, Patil N, Cioffi G, Waite K, Kruchko C, Barnholtz-Sloan
JS.
CBTRUS
Statistical Report: Primary Brain and Other Central Nervous System
Tumors Diagnosed in the United States in 2013-2017.
Neuro
Oncol. 2020 Oct 30, 2020;22(Suppl
1):iv1–iv96.ˍ.
doi: 10.1093/neuonc/noaa200∟.
PMID: 33123732∟.
Observational
study. ˍ
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Ferguson
SD, Hodges TR, Majd NK, Alfaro-Munoz K, Al-Holou WN, Suki D, de
Groot JF, Fuller GN, Xue L, Li M, Jacobs C, Rao G, Colen RR, Xiu
J, Verhaak R, Spetzler D, Khasraw M, Sawaya R, Long JP, Heimberger
AB.
A
validated integrated clinical and molecular glioblastoma long-term
survival-predictive nomogram.
Neurooncol
Adv. 2020 Oct 31, 2021;3(1):vdaa146∟.
doi: 10.1093/noajnl/vdaa146∟.
PMID: 33426529∟.
Observational
study.
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