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Glioblastoma | Etiopathogenesis | Microenvironment | Immunosuppression

Home > Publications > Topics > Glioblastoma > Etiopathogenesis > Microenvironment > Immunosuppression

2025

Nicolaou N, Andreou MS, Neophytou CM, Papageorgis P.
Emerging insights into the immunosuppressive tumor microenvironment and its implications for glioblastoma immunotherapy.
Front Immunol. 2025 Oct 24;16:1665742. doi: 10.3389/fimmu.2025.1665742. PMID: 41208963. Review. ˍ

Wei Y, Shi Y, Wang H, Shang Y, Yu B, Zhang Y.
Glioblastoma insights: Focus on crosstalk with the suppressive tumor microenvironment and advanced therapeutic strategies.
Medicine (Baltimore). 2025 Dec 5;104(49):e46285. doi: 10.1097/MD.0000000000046285. PMID: 41366964. Review. ˍ

Pang C, Wang Y.
The Immunosuppressive Microenvironment of Glioblastoma: Mechanisms, Clinical Challenges and Future Directions.
Immunology. 2025 Dec 19. doi: 10.1111/imm.70087. PMID: 41414954. Review. ˍ

2026

Figg JW, Flores CT.
Rewriting microenvironment immunity in glioblastoma.
Mol Ther Oncol. 2026 Jun 9;34(2):201245. doi: 10.1016/j.omton.2026.201245. PMID: 42291139. ˍ

Yang J, Li J, Jin M, Lu Y, Zhang L.
The immunosuppressive tumor microenvironment in glioblastoma.
Front Immunol. 2026 Jul 2;17:1806996. doi: 10.3389/fimmu.2026.1806996. PMID: 42465775. ˍ

Omene E.
Metabolic cell competition in the glioblastoma tumour microenvironment: glucose, glutamine, and lactate as determinants of immune exclusion and targets for pharmacological reprogramming.
Front Oncol. 2026 Jul 14;16:1849888. doi: 10.3389/fonc.2026.1849888. PMID: 42523684. ˍ

Aydın HA, Keskin E, Kalaycı M.
Reprogramming the immunosuppressive microenvironment in glioblastoma: the microglia-MDSC-Treg axis and translational therapeutic strategies.
Front Oncol. 2026 Aug 10;16:1782775. doi: 10.3389/fonc.2026.1782775. PMID: 42639384. ˍ

Souat S, El Azhary K, Bourdoukh S, Kone AS, Qandouci A, Harmak Z, Choukri K, Lakhdar A, Badou A.
Elevated BTLA Expression Correlates with an Immunosuppressive Microenvironment and Defines Dysfunctional Circulating T Cells in Human Glioblastoma.
Med Sci (Basel). 2026 Jul 25;14(4):433. doi: 10.3390/medsci14040433. PMID: 42646567. ˍ