Topics
Glioblastoma | Treatment | Clinical trials | Viruses
Home > Publications > Topics > Glioblastoma > Treatment > Clinical trials > Viruses
*Rossmeisl JH, King JN, Robertson JL, Weger-Lucarelli J,
Elankumaran S.
Phase I/II Trial of
Urokinase Plasminogen Activator-Targeted Oncolytic Newcastle
Disease Virus for Canine Intracranial Tumors.
Cancers
(Basel). 2024 Jan 29;16(3):564. doi:
10.3390/cancers16030564. PMID:
38339315. Interventional animal study. ˍ
Gunasegaran B, Ashley CL,
Marsh-Wakefield F, Guillemin GJ, Heng B.
Viruses
in glioblastoma:
an update on evidence and clinical trials.
BJC
Rep. 2024 Apr
19;2(1):33. doi:
10.1038/s44276-024-00051-z.
PMID:
39516641. Review. ˍ
Daftari M, Ramsoomair CK, Aaronson D, Seetharam D, Andreae EA,
Wright L, Han S, Chandar J, Lu V, Govindarajan V, Ivan ME, Komotar
RJ, de la Fuente M, Shah AH.
Synergistic
Treatment with Antiretrovirals and Laser Interstitial Thermal
ThErapy (STARLITE) for unresectable glioblastoma: A phase 1 study
protocol.
PLoS
One. 2025 Aug 28;20(8):e0328204. doi:
10.1371/journal.pone.0328204. PMID:
40875628. Interventional study protocol. ˍ
Zeng W, Wang P, Fang S, Ge S, Jia W, Peng S, Wang M, Qin X, Zhang
W, Gao J, Su X, Yuan G, Wu J, Liu Y, Wang Y, Lu H, Mu R, Wu F,
Chang Q, Jin G, Meng F, Zhang J, Liu F.
ON-01,
an engineered recombinant oncolytic herpes simplex virus type-1,
in recurrent glioma: a single-arm, phase 1/2 study.
Neuro
Oncol. 2026 Jan 12:noag005. doi:
10.1093/neuonc/noag005. PMID:
41527280.
Interventional study. ˍ
Ene CI, Singh S, Venkataraman T, Phillips LM, Long JP, Singh D,
Tran ND, Tufaro F, Anand PJ, Navin N, Prabhu S, Weinberg JS,
Larman HB, Gomez-Manzano C, Fueyo J, Lang FF.
Systemic
immune correlates of long-term survival after Delta-24-RGD based
on the Therapeutic Adenovirus for Recurrent Glioblastoma Effect
Trial (TARGET).
Clin
Cancer Res. 2026 Jan 29. doi:
10.1158/1078-0432.CCR-25-3566. PMID:
41609523. Interventional study˰
ˍ
Meylan M, Tian Y, Wu L, Ling AL, Kovarsky D, Barlow GL, Nguyen LD,
Pyrdol J, Marx S, Westphal L, Michel J, Gonzalez Castro LN, Dumont
S, Santos A, Tirosh I, Suvà ML, Chiocca EA, Wucherpfennig
KW.
Persistent T cell activation and
cytotoxicity against glioblastoma following single oncolytic virus
treatment in a clinical trial.
Cell.
2026 Feb 11;189(5):1287-1304.e18. doi:
10.1016/j.cell.2025.12.055. PMID:
41679299. Interventional study.
ˍ