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High-grade gliomas | Treatment | Clinical trials | Margins




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Qiu Y, Li Y, Cuihong J, Wu X, Liu W, Fan C, Ye X, He L, Xiao S, Zhao Q, Wu W, Chen K, Tan C, Li Y, Wang H, Liu F.
Toxicity and Efficacy of Different Target Volume Delineations of Radiotherapy Based on the Updated RTOG/NRG and EORTC Guidelines in Patients with Grade 3-4 Glioma: A Randomized Controlled Clinical Trial.
Int J Radiat Oncol Biol Phys. 2024 Nov 28:S0360-3016(24)03668-X. doi: 10.1016/j.ijrobp.2024.11.094. PMID: 39615657. Interventional study˰ ˍ




Zhong L, Zhou P, Chen L, Chen D, Wen L, Diao X, Zhang A, Gao Y, Chen G, Li X, Huang S, Niu K, Pei Y, Liu G, Lv S, Li G. Modified Target Delineation and Moderately Hypofractionated Radiotherapy for High-Grade Glioma: A Randomized Clinical Trial. JAMA Netw Open. 2025 Jul 1;8(7):e2523053. doi: 10.1001/jamanetworkopen.2025.23053. PMID: 40705330. Interventional study. ˍ ChiCTR.org.cn ID: ChiCTR1800014396.




Anvari K, Javadinia SA, Fazilatpanah D, Esmaily H, Aledavood SA, Shahidsales S, Ganjeifar B, Dayani M, Rabiei P.
Comparing the Recurrence Patterns of Reduced-Margins vs. RTOG-Protocol in Adjuvant Chemoradiation of High-Grade Gliomas: A Multicenter, Open-Label, Randomized Controlled Trial.
Asian Pac J Cancer Prev. 2026 Jun 18;27(6):2005-2013. doi: 10.31557/APJCP.2026.27.6.2005. PMID: 42345146. Trial registration ID: IRCT20210215050367N1. ˍ