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Pediatric-type diffuse high-grade gliomas | Treatment | Immunotherapy | Vaccines
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Thompson EM, Ashley DM, Ayasoufi K, Norberg P, Archer G, Buckley
ED, Herndon JE 2nd, Walter A, Archambault B, Flahiff C, Jaggers D,
Gorski L, Sanchez LA, Congdon K, Hotchkiss K, Cook SL, Moelker E,
Vlahovic G, Reap E, Schroeder K, Randazzo D, Desjardins A, Johnson
MO, Peters K, Khasraw M, Friedman H, Mitchell DA, Sampson JH,
Landi D.
A peptide vaccine targeting
the CMV antigen pp65 in children and young adults with recurrent
high-grade glioma and medulloblastoma: a phase 1 trial.
Nat
Cancer. 2025 Jun 12. doi:
10.1038/s43018-025-00998-z. PMID:
40506525. Interventional study˰
ˍ
Harper SD, Alderete JA, Baisiwala S, Bergsneider BH, Liau LM, Wang
AC.
Vaccine therapy for pediatric
high-grade glioma: current landscape, challenges, and future
directions.
J
Neurooncol. 2026 Jan 8;176(2):158. doi:
10.1007/s11060-025-05403-4. PMID:
41504830. Review. ˍ