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Glioblastoma | Etiopathogenesis | Resistance
Home > Publications > Topics > Glioblastoma > Etiopathogenesis > Resistance
Piccirillo SG, Spiteri I, Sottoriva A, Touloumis A, Ber S, Price
SJ, Heywood R, Francis NJ, Howarth KD, Collins VP, Venkitaraman
AR, Curtis C, Marioni JC, Tavaré S, Watts C.
Contributions
to drug resistance in glioblastoma derived from malignant cells in
the sub-ependymal zone.
Cancer
Res. 2014 Nov 18;75(1):194-202. doi:
10.1158/0008-5472.CAN-13-3131. PMID:
25406193. Laboratory investigation. ˍ
Chang
C, Chavarro VS, Gerstl JVE, Blitz SE, Spanehl L, Dubinski D,
Valdes PA, Tran LN, Gupta S, Esposito L, Mazzetti D, Gessler FA,
Arnaout O, Smith TR, Friedman GK, Peruzzi P, Bernstock JD.
Recurrent
Glioblastoma-Molecular Underpinnings and Evolving Treatment
Paradigms.
Int
J Mol Sci.
2024 Jun 19;25(12):6733. doi:
10.3390/ijms25126733. PMID:
38928445.
Review. ˍ
Palizkaran
Yazdi M, Barjasteh A, Moghbeli M.
MicroRNAs
as the pivotal regulators of Temozolomide resistance in
glioblastoma.
Mol
Brain.
2024 Jul 2;17(1):42. doi:
10.1186/s13041-024-01113-6. PMID:
38956588. Review. ˍ
Sherman JH, Bobak A, Arsiwala T, Lockman P, Aulakh S.
Targeting
drug resistance in glioblastoma (Review).
Int
J Oncol. 2024 Jul 9;65(2):80. doi:
10.3892/ijo.2024.5668. PMID:
38994761.
Review. ˍ
Pathikonda S, Amirmahani F, Mathew D, Muthukrishnan SD.
Histone
acetyltransferases as promising therapeutic targets in
glioblastoma resistance.
Cancer
Lett. 2024 Sep 24;604:217269. doi:
10.1016/j.canlet.2024.217269. PMID:
39326554. Review. ˍ
Alshammari QA, Alshammari SO, Alshammari A, Alfarhan M, Baali FH.
Unraveling the mechanisms of
glioblastoma's resistance: investigating the influence of tumor
suppressor p53 and non-coding RNAs.
Naunyn
Schmiedebergs Arch Pharmacol. 2024 Oct 30. doi:
10.1007/s00210-024-03564-z. PMID:
39476245. Review˰ ˍ
Kricha A, Bouchmaa N, Ben Mkaddem S, Abbaoui A, Ben Mrid R, El
Fatimy R.
Glioblastoma-associated
macrophages: A key target in overcoming glioblastoma therapeutic
resistance.
Cytokine
Growth Factor Rev. 2024 Oct 31:S1359-6101(24)00088-1.
doi:
10.1016/j.cytogfr.2024.10.009. PMID:
39510901. Review. ˍ
Sørensen MD, Olsen RFS, Burton M, Kavan S, Petterson SA,
Thomassen M, Kruse TA, Meyer M, Kristensen BW.
Microglia
induce an interferon-stimulated gene expression profile in
glioblastoma and increase glioblastoma resistance to
temozolomide.
Neuropathol
Appl Neurobiol. 2024 Nov 18;50(6):e13016. doi:
10.1111/nan.13016. PMID:
39558550. Laboratory investigation. ˍ
Wu H, Gao W, Chen P, Wei Y, Zhao H, Wang F.
Research
progress of drug resistance mechanism of temozolomide in the
treatment of glioblastoma.
Heliyon.
2024 Oct 30;10(21):e39984. doi:
10.1016/j.heliyon.2024.e39984. PMID:
39568843. Review. ˍ
Bou-Gharios J, Noël G, Burckel H.
The
neglected burden of chronic hypoxia on the resistance of
glioblastoma multiforme to first-line therapies.
BMC
Biol. 2024 Nov 28;22(1):278. doi:
10.1186/s12915-024-02075-w. PMID:
39609830. Review. ˍ
Xue J, Zhang J, Zhu J.
Unraveling
molecular signatures and prognostic biomarkers in glioblastoma: a
comprehensive study on treatment resistance and personalized
strategies.
Discov
Oncol. 2024 Dec 4;15(1):743. doi:
10.1007/s12672-024-01649-y. PMID:
39630160. Observational study. ˍ
Arefnezhd R, Chahardehi AM, Asadi A, Shadravan MM, Shariati A,
Rezaee A, Radmanesh M, Nazarian M, Helfi M, Soleimani Meigoli MS,
Motedayyen H, Rezaei-Tazangi F, Tavakoli MR.
The
function of chaperones in the radioresistance of glioblastoma: a
new insight into the current knowledge.
Brain
Tumor Pathol. 2025 Apr 21. doi:
10.1007/s10014-025-00501-7. PMID:
40259161. Review˰ ˍ
Ghosh N, Chatterjee D, Datta A.
Tumor
heterogeneity and resistance in glioblastoma: the role of stem
cells.
Apoptosis.
2025 May 15. doi:
10.1007/s10495-025-02123-y. PMID:
40375039. Review. ˍ
Chen
Y, Ding K, Zheng S, Gao S, Xu X, Wu H, Zhou F, Wang Y, Xu J, Wang
C, Ling C, Xu J, Wang L, Wu Q, Giamas G, Chen G, Zhang J, Yi C, Ji
J.
Post-translational
modifications in DNA damage repair: mechanisms underlying
temozolomide resistance in glioblastoma.
Oncogene.
2025 May 26;44(23):1781-1792. doi:
10.1038/s41388-025-03454-5. PMID:
40419791. Review. ˍ
Shah S, Lucke-Wold B.
Cell-Intrinsic
and Cell-Extrinsic Therapeutic Targets in Glioblastoma: Overcoming
Resistance Through Tumor Microenvironment Modulation and Precision
Medicine.
World
Neurosurg. 2025 Jun 4:124142. doi:
10.1016/j.wneu.2025.124142. PMID:
40480545. Review. ˍ
Beylerli O, Gareev I, Musaev E, Ilyasova T, Roumiantsev S,
Chekhonin V.
Angiogenesis and
Resistance Mechanisms in Glioblastoma: Targeting Alternative
Vascularization Pathways to Overcome Therapy Resistance.
Curr
Pharm Des. 2025 Jul 22. doi:
10.2174/0113816128367551250703122830. PMID:
40698688.
Review˰
ˍ
Husain A, Ahmad F, Pandey S, Upadhyay TK, Kang S, Choi M, Choi J,
Park MN, Kim B.
Progenitor cells,
microglia, and non-coding RNAs: Orchestrators of glioblastoma
pathogenesis and therapeutic resistance.
Noncoding
RNA Res. 2025 Aug 5;15:85-99. doi:
10.1016/j.ncrna.2025.07.007. PMID:
40896358. Review. ˍ
Tremante E, Díaz Méndez AB, Rizzo MG.
The
Role of LncRNAs in Radio- and Chemoresistance of Glioblastoma:
Prognostic or Therapeutic?
Curr
Oncol. 2025 Sep 27;32(10):539. doi:
10.3390/curroncol32100539. PMID:
41149459. Review. ˍ
*Wu Y, Ren Y, Li S, Zeng M, Wang J, Li M, Peng Y.
Association
between intraoperative hypotension during brain tumor resection
and postoperative delirium: A secondary analysis of a randomized
controlled trial.
PLoS
One. 2025 Oct 29;20(10):e0334094. doi:
10.1371/journal.pone.0334094. PMID:
41160633. Interventional study. ˍ
*Durga YK, Pusapati RV.
Drug
resistance in glioblastoma: Challenges, mechanisms and therapeutic
strategies (Review).
Mol
Clin Oncol. 2025 Nov 6;24(1):4. doi:
10.3892/mco.2025.2913. PMID:
41281928. Review. ˍ
Khafaga DSR, Basem Y, AlAtar HM, Sherif A, Ata A, Sabry F,
El-Morsy MT, Attia SS.
Cancer
Neuroscience: Linking Neuronal Plasticity with Brain Tumor Growth
and Resistance.
Biology
(Basel). 2026 Jan 6;15(2):108. doi:
10.3390/biology15020108. PMID:
41594844. Review. ˍ
Wisdom AJ, Temple H, Cui Y, Del Vecchio CT, Kim T, White FM, Floyd
SR, Spranger S. Mechanisms,
Microenvironments,
and Models: Understanding Therapeutic Resistance in Glioblastoma.
Int
J Radiat Oncol Biol Phys. 2026 Apr
22:S0360-3016(26)00587-0. doi:
10.1016/j.ijrobp.2026.04.013. PMID:
42031225. ˍ
Li W, Jiang S, Liu K, Li Z, Yang J, Liu W, Huang Y, Yang M, Guo S,
Ruan S.
Exosome
Secretion Drives Chemo-Resistance of Temozolomide in Glioblastoma.
J
Extracell Biol. 2026 Jun 30;5(7):e70161. doi:
10.1002/jex2.70161. PMID:
42383157. ˍ
Achari E, Ahmady-Nield F, Sharma A, Schmidt-Wolf IGH, Maciaczyk J,
Luwor RB, Achuthan AA.
Mechanisms of
Therapeutic Resistance and Recent Advances in Glioblastoma
Treatment.
Immunol
Cell Biol. 2026 Jul 3. doi:
10.1111/imcb.70144. PMID:
42396877. ˍ