Neuro-Oncology Reviews

Volume 27 Number 36
31 December 2025

Home > Publications > Neuro-Oncology Reviews > Volume 27, Year 2025 > Number 36, 31 December

Pérez-Alfayate R, Paz-Cabezas M, Pérez-Segura P, Sanchez Del Hoyo R, Cabezas-Camarero S.
Cerebrospinal fluid ctDNA as a diagnostic and prognostic tool in gliomas: a systematic review and meta-analysis.
Front Oncol. 2025 Dec 11;15:1714287. doi: 10.3389/fonc.2025.1714287. PMID: 41458584. Review; Meta-analysis. ˍ

Podder V, Sarfraz Z, Qidwai KA, Maharaj A, Ranjan T, Aulakh S, Ahluwalia MS.
Gaps in Diagnosis, Treatment, and Outcomes Among Patients with Brain Tumors in the United States: A State-of-the-Art Review. Cancers (Basel). 2025 Dec 13;17(24):3982. doi: 10.3390/cancers17243982. PMID: 41463231. Review. ˍ

Flores T, Delpierre E, Male G, Gourin C, Hantz S, Damour A, Ligat G.
Targeting Human Cytomegalovirus as a Novel Approach for Glioblastoma Treatment.
Pathogens. 2025 Dec 16;14(12):1291. doi: 10.3390/pathogens14121291. PMID: 41471245. Review. ˍ

Królikowska K, Błaszczak K, Ławicki S, Zajkowska M, Gudowska-Sawczuk M.
Glioblastoma-A Contemporary Overview of Epidemiology, Classification, Pathogenesis, Diagnosis, and Treatment: A Review Article.
Int J Mol Sci. 2025 Dec 18;26(24):12162. doi: 10.3390/ijms262412162. PMID: 41465586. Review. ˍ

Nakhaei A, Afshari S, Mohammadian M, Ahmadi SS, Mohatshami E, Jalili-Nik M, Jalali M, Karav S, Afshari AR, Kesharwani P, Sahebkar A.
Harnessing the role of insulin-like growth factor in glioblastoma: a comprehensive review.
Neuroscience. 2025 Dec 19;594:172-186. doi: 10.1016/j.neuroscience.2025.12.044. PMID: 41423020. Review˰ ˍ

Gerritsen JKW, Karschnia P, Bello L, Hervey-Jumper S, Young JS, Seidel K, Satoer DD, Schnell O, Parsons M, Nahed BV, Menna G, Teske N; External Rater Panel; Smith TR, Sanai N, Krieg SM, Schucht P, Broekman MLD, De Vleeschouwer S, Jakola AS, van den Bent MJ, Chang SM, Vogelbaum MA, Vincent AJPE, Tonn JC, Berger MS.
A comprehensive framework for glioma surgery by the PIONEER Consortium and RANO resect group, part 1: intraoperative recommendations for mapping, monitoring, and decision making.
Lancet Oncol. 2025 Dec 22;27(1):e11-e23. doi: 10.1016/S1470-2045(25)00531-5. PMID: 41449153. Guidelines˰ ˍ

Gerritsen JKW, Karschnia P, Bello L, Hervey-Jumper S, Young JS, Seidel K, Satoer DD, Schnell O, Parsons M, Nahed BV, Menna G, Teske N; External Rater Panel; Smith TR, Sanai N, Krieg SM, Schucht P, Broekman MLD, De Vleeschouwer S, Jakola AS, van den Bent MJ, Chang SM, Vogelbaum MA, Vincent AJPE, Tonn JC, Berger MS.
A comprehensive framework for glioma surgery by the PIONEER Consortium and RANO resect group, part 2: perioperative recommendations for neurological, language, functional, and quality-of-life assessment.
Lancet Oncol. 2025 Dec 22;27(1):e24-e32. doi: 10.1016/S1470-2045(25)00532-7. PMID: 41449155. Guidelines˰ ˍ

Cui S, Guan F, Li X, Long X, Wu M.
Astrocytes in glioblastoma tumor microenvironment.
Biochim Biophys Acta Rev Cancer. 2025 Dec 23;1881(1):189518. doi: 10.1016/j.bbcan.2025.189518. PMID: 41448554. Review˰ ˍ

Li B, Xi W, Li P.
Cytotoxic T lymphocytes and their dual role in modulating blood-brain barrier integrity in immune-mediated neurological pathologies.
J Transl Med. 2025 Dec 23. doi: 10.1186/s12967-025-07288-3. PMID: 41437267. Review. ˍ

Agarwal S.
Cancer neuroscience: illuminating the neural dimension of tumor biology.
Sci Rep. 2025 Dec 24;15(1):44406. doi: 10.1038/s41598-025-31931-0. PMID: 41436803. Editorial. ˍ

Stepniak A, Diamandi J, Shanahan RM, Garcia J, Qazi Z, Cabral DTF, Agarwal N, Hamilton DK.
Mapping influence in pediatric craniopharyngioma: the 50 most cited articles.
Childs Nerv Syst. 2025 Dec 25;41(1):432. doi: 10.1007/s00381-025-07071-1. PMID: 41447417. Bibliometric analysis˰ ˍ

Liu J, Ha JH, Abikenari M, Sjoholm MA, Annagiri S, Ravi K, Bergsneider BH, Verma R, Theodros D, Medikonda R, Li G, Prolo LM, Monje M, Lim M.
Adaptive immunotherapeutic paradigms in diffuse midline glioma: integrating epigenetic reprogramming, neuron-glioma interactions, and tumor microenvironment modulation.
J Neurooncol. 2025 Dec 29;176(2):144. doi: 10.1007/s11060-025-05347-9. PMID: 41460355. Review. ˍ

St Brice K, Parker T, Wouters K, Guzmán-Ríos ED, Marciscano AE, Wang N, Dietrich J, Choi BD, Nahed BV.
Extent of resection and adjuvant treatment in adult cerebellar glioblastoma: systematic review and meta-analysis of survival outcomes.
J Neurooncol. 2025 Dec 29;176(2):138. doi: 10.1007/s11060-025-05390-6. PMID: 41460384. Review; Meta-analysis˰ ˍ

Parikh D, Shah M.
Targeting non-coding RNAs to overcome resistance and improving outcomes in glioblastoma.
Glob Med Genet. 2025 Sep 10;12(4):100075. doi: 10.1016/j.gmg.2025.100075. PMID: 41451392. Review. ˍ

Fares J, Wan Y, Li Y, Matys T, Carpenter TA, Price SJ.
Magnetic Resonance Imaging Physics in Brain Tumor Imaging: A Primer for Neurosurgeons.
World Neurosurg. 2025 Oct 24;204:124591. doi: 10.1016/j.wneu.2025.124591. PMID: 41429737. Review. ˍ

Geens W, Rizani G, Del Gaudio N, Buyck F, Van Gestel F, Bruneau M, Neyns B, Duerinck J.
Extent of resection and its association with overall survival in newly diagnosed IDH wildtype glioblastoma treated with concomitant radiochemotherapy: a systematic review and meta-analysis.
Brain Spine. 2025 Nov 21;5:105867. doi: 10.1016/j.bas.2025.105867. PMID: 41450869. Review; Meta-analysis. ˍ

Lombardi G, Baro V, Landi A.
Adult Gliomas: From Molecular Insight to Clinical Horizons.
Curr Oncol. 2025 Nov 24;32(12):659. doi: 10.3390/curroncol32120659. PMID: 41440187. Editorial. ˍ

Mehfooz M, Raza H, Javed A, Ejaz Y.
CAR-T in Central Nervous System Tumours: Promising Science, Slow Clinical Progress.
Clin Oncol (R Coll Radiol). 2025 Nov 24;49:103986. doi: 10.1016/j.clon.2025.103986. PMID: 41442796. Perspective. ˍ

Himic V, Ramsoomair CK, Soldozy S, Komotar RJ, Ivan ME, Shah AH.
The Future of Clinical Trials in Surgical Neuro-Oncology Is Bright.
Brain Sci. 2025 Nov 27;15(12):1274. doi: 10.3390/brainsci15121274. PMID: 41440070. Editorial. ˍ

Sarpong EO, Sokotukhin V, Egermann H, Mueller A, Konan LM.
Glioblastoma Multiforme Occurring After 20 Years at the Resection Site of Cerebral Arteriovenous Malformation: A Case Report and Literature Review.
Cureus. 2025 Nov 27;17(11):e97919. doi: 10.7759/cureus.97919. PMID: 41458749. Case report; Review. ˍ

Mebrahtu AK, Jain V, Moelker EM, Hoyt-Miggelbrink AM, Ayasoufi K, Thompson EM.
Peptide Vaccines for Pediatric High-Grade Glioma and Diffuse Midline Glioma: Current Progress and Future Perspectives.
Vaccines (Basel). 2025 Nov 30;13(12):1215. doi: 10.3390/vaccines13121215. PMID: 41441679. Review. ˍ

Shah N, Sohl J, Ganassi M, Guglielmi L, Badodi S.
Challenges and Innovations in Paediatric Brain Tumour Treatments.
Pharmaceutics. 2025 Dec 3;17(12):1561. doi: 10.3390/pharmaceutics17121561. PMID: 41471075. Review. ˍ

Colangelo T, Saponaro AA, Mazzoccoli G, Serviddio G, Villani R.
Emerging Frontiers in Neuro-Oncology: Insights into Extracellular Vesicle-Driven Tumor Mechanisms and Nanotherapeutic Strategies.
Int J Mol Sci. 2025 Dec 7;26(24):11826. doi: 10.3390/ijms262411826. PMID: 41465256. Review. ˍ

Markopoulos GS, Sioka C, Alexiou GA, Peschos D, Vartholomatos G, Kyritsis AP.
Natural Anti-Inflammatory Agents in the Chemoprevention of Gliomas: Targeting Neuroinflammation and the Tumor Microenvironment.
Cancers (Basel). 2025 Dec 8;17(24):3922. doi: 10.3390/cancers17243922. PMID: 41463173. Review. ˍ

Chung J, Saad J, Kafri A, Rossignol J, Verbrugge M, Bakke J.
Metabolism of glioblastoma: a review of metabolic adaptations and metabolic therapeutic interventions.
Front Oncol. 2025 Dec 10;15:1712576. doi: 10.3389/fonc.2025.1712576. PMID: 41450919. Review. ˍ

Liu J, Wang Y, Su S, Cheng G, Zhao H, Sun J, Sun G, Li F, Hui R, Liu M, Wu L, Wu D, Yang F, Dang Y, Hei J, Li Y, Gao Z, Wang B, Bai Y, Lv W, Zhang J.
Oncolytic Viruses in Glioblastoma: Clinical Progress, Mechanistic Insights, and Future Therapeutic Directions.
Cancers (Basel). 2025 Dec 10;17(24):3948. doi: 10.3390/cancers17243948. PMID: 41463198. Review. ˍ