Neuro-Oncology Reviews




Volume 27 Number 35
20 December 2025




Home > Publications > Neuro-Oncology Reviews > Volume 27, Year 2025 > Number 35, 20 December






Drappatz J, Mantica M.
Treatment strategies and innovation for recurrent high-grade glioma.
J Neurooncol. 2025 Dec 11;176(1):118. doi: 10.1007/s11060-025-05323-3. PMID: 41381983. Review˰ ˍ




Drapkin AJ.
On the question of prognosis in cystic gliomas.
World Neurosurg. 2025 Dec 11:124714. doi: 10.1016/j.wneu.2025.124714. PMID: 41390081. Perspective. ˍ




McKerill E, Tan JK, Rao CK, Linares CA, Banerjee S, Rabbani RD, Adeleke S, Ghose A, Boussios S.
Efficacy of ketogenic metabolic therapy as an adjuvant to the current standard of care in the treatment of glioblastoma: A systematic review of clinical trials.
Med Oncol. 2025 Dec 11;43(1):49. doi: 10.1007/s12032-025-03165-7. PMID: 41379280. Review. ˍ




Pérez-Alfayate R, Paz-Cabezas M, Pérez-Segura P, Sanchez Del Hoyo R, Cabezas-Camarero S.
Cerebrospinal fluid ctDNA as a diagnostic and prognostic tool in gliomas: a systematic review and meta-analysis.
Front Oncol. 2025 Dec 11;15:1714287. doi: 10.3389/fonc.2025.1714287. PMID: 41458584. Review; Meta-analysis. ˍ




Ehret F, Rogers CL, Fontanesi J, Wilson GD, Chitti BS, Starner J, Sidiqi B, Goenka A, Schulder M, Bruynzeel AME, Verhoeff JJC, MacDonagh AC, Park HI, Shih HA, Kleinberg L.
Radiation Therapy for Non-Malignant Central Nervous System Tumors, Disorders, and Illnesses - Current Applications and Future Directions.
Semin Radiat Oncol. 2025 Dec 12;36:77-94. doi: 10.1016/j.semradonc.2025.08.005. PMID: 41391900. Review. ˍ




Scagliotti E, Capetti B, Conti L, Fiore G, Fanizzi C, Bertani G, Pravettoni G, Locatelli M.
Effects of proton therapy on cognition in adults with brain tumors: a systematic review.
J Neurooncol. 2025 Dec 12;176(1):121. doi: 10.1007/s11060-025-05371-9. PMID: 41385035. Review˰ ˍ




Jia L, Chen Y, Li H, Zhao K, Ge S, Wang C, Zhao J, Li F, Zhang L, Yao A.
The glymphatic system in neurodegenerative diseases and brain tumors: mechanistic insights, biomarker advances, and therapeutic opportunities.
Acta Neuropathol Commun. 2025 Dec 13. doi: 10.1186/s40478-025-02203-9. PMID: 41390476. Review. ˍ




Karsonovich T, Gasalberti DP, Rayi A.
Low-Grade Gliomas.
StatPearls Publishing, Treasure Island (FL), 2025 Dec 13. PMID: 32809503. Bookshelf ID: NBK560668. Book. ˍ




Love CA, Figg JW, Engelbart M, West I, Flores C.
Radial glial cells and glioblastoma: how developmental neurobiology can inform our understanding of brain cancer initiation, treatment resistance, and resilience.
Transl Oncol. 2025 Dec 13;64:102645. doi: 10.1016/j.tranon.2025.102645. PMID: 41391380. Review. ˍ




Podder V, Sarfraz Z, Qidwai KA, Maharaj A, Ranjan T, Aulakh S, Ahluwalia MS.
Gaps in Diagnosis, Treatment, and Outcomes Among Patients with Brain Tumors in the United States: A State-of-the-Art Review. Cancers (Basel). 2025 Dec 13;17(24):3982. doi: 10.3390/cancers17243982. PMID: 41463231. Review. ˍ




Boffelli L, Fimiani C, Núñez NG, Kienzler JC.
Synergy of radiotherapy, focused ultrasound, and immunotherapy in the treatment of brain metastases.
J Neurooncol. 2025 Dec 15;176(1):124. doi: 10.1007/s11060-025-05379-1. PMID: 41396538. Review. ˍ




Wong ET, Lok E.
Transnasal drug delivery to the brain: circumventing barriers for brain tumor patients.
Am J Transl Res. 2025 Dec 15;17(12):9466-9477. doi: 10.62347/BERU9082. PMID: 41552350. Review. ˍ




Flores T, Delpierre E, Male G, Gourin C, Hantz S, Damour A, Ligat G.
Targeting Human Cytomegalovirus as a Novel Approach for Glioblastoma Treatment.
Pathogens. 2025 Dec 16;14(12):1291. doi: 10.3390/pathogens14121291. PMID: 41471245. Review. ˍ




Sadhasivam S, Velpula S, Prasanna L, Arora RK, Menon G, Nair SN.
Impact of awake mapping on extent of resection and neurological outcomes of Low-grade gliomas: a systematic review and Meta-analysis.
Neurosurg Rev. 2025 Dec 16;49(1):74. doi: 10.1007/s10143-025-03998-w. PMID: 41398134. Review; Meta-analysis˰ ˍ




Wang B, Li C, Gu J, Wang X, Xun M, Jiang B, Yan J.
Targeting glioma-associated microglia and macrophages: a new frontier in glioblastoma immunotherapy.
Front Immunol. 2025 Dec 17;16:1726440. doi: 10.3389/fimmu.2025.1726440. PMID: 41479886. Review. ˍ




Królikowska K, Błaszczak K, Ławicki S, Zajkowska M, Gudowska-Sawczuk M.
Glioblastoma-A Contemporary Overview of Epidemiology, Classification, Pathogenesis, Diagnosis, and Treatment: A Review Article.
Int J Mol Sci. 2025 Dec 18;26(24):12162. doi: 10.3390/ijms262412162. PMID: 41465586. Review. ˍ




Al Sharie S, Sawaftah K, Qasim H, Al-Hussaini M.
Methylation profiling in neuropathological tumors diagnosis: a comprehensive review.
Front Oncol. 2025 Dec 19;15:1720458. doi: 10.3389/fonc.2025.1720458. PMID: 41487568. Review. ˍ




Eibl RH, Schneemann M.
Circulating Tumor Cells in Glioblastoma.
Cancers (Basel). 2025 Dec 19;18(1):10. doi: 10.3390/cancers18010010. PMID: 41514523. Review. ˍ




Nakhaei A, Afshari S, Mohammadian M, Ahmadi SS, Mohatshami E, Jalili-Nik M, Jalali M, Karav S, Afshari AR, Kesharwani P, Sahebkar A.
Harnessing the role of insulin-like growth factor in glioblastoma: a comprehensive review.
Neuroscience. 2025 Dec 19;594:172-186. doi: 10.1016/j.neuroscience.2025.12.044. PMID: 41423020. Review˰ ˍ




Pang C, Wang Y.
The Immunosuppressive Microenvironment of Glioblastoma: Mechanisms, Clinical Challenges and Future Directions.
Immunology. 2025 Dec 19. doi: 10.1111/imm.70087. PMID: 41414954. Review. ˍ




Raja M, Quintero G, Lone YC, Trojan J.
Impact of Nanotechnology on Glioblastoma Studies: From Brain Stem Cells to Neoplastic Development and Cancer Gene Therapy.
Front Biosci (Elite Ed). 2025 Dec 19;17(4):38600. doi: 10.31083/FBE38600. PMID: 41504090. Review. ˍ